McGowan Institute for Regenerative Medicine

Liz Reid / 90.5 WESA

Every year in the U.S., 200,000 people get pacemakers, 600,000 get knee replacements and 2.5 million have surgery to implant artificial eye lenses to fix cataracts. But the medical community knows little about how the aging process affects these implantable medical devices.

Bryan Brown wants to change that.

He’s a professor of bioengineering at the University of Pittsburgh, and he’s trying to figure out how to harness the immune system’s natural inflammatory response to better integrate these devices into the body.

Mark Nootbaar / 90.5 WESA

Artificial lungs have been around for decades, but they’re usually large devices that force the patient to remain in a hospital bed until their lungs improve or they’re able to undergo a lung transplant. 

But University of Pittsburgh Medical Devices Laboratory Director Bill Federspiel has developed a more mobile, wearable device.