University of Pittsburgh School of Medicine

Hoping to increase the number of successful liver transplants, a new organ preservation system is being tested which uses what’s called a “machine perfusion” technique.

Researchers at the University of Pittsburgh School of Medicine say the new system pumps cooled, oxygen-rich fluid into donor livers. This keeps the organs in excellent condition for up to nine hours before transplantation.

When it comes to protecting those most vulnerable to influenza, a high-dose flu vaccine may be most effective.

That’s according to the findings of a study from the University of Pittsburgh School of Medicine which found that giving a high-dose vaccine to elderly people in long-term care facilities helped build immunity. Each year in the U.S. there are 3,000 to 49,000 influenza-related deaths.

There are four automatic external defibrillators (AEDs) in the Pittsburgh City-County Building, and more than 70 on the campus of Carnegie Mellon University, but how many are in Allegheny County? That’s what the University of Pittsburgh’s School of Medicine wants to know.

The school is hosting the region’s first HeartMap Challenge, a public scavenger hunt to locate all of the county’s AEDs, which are small briefcase-sized electronic devices that can be used to help someone in cardiac arrest.

The University of Pittsburgh School of Medicine has developed a 91 percent accurate genetic test to identify those patients whose prostate cancer is likely to recur. The new knowledge may lead to a clinical test, as well as future drugs and therapies.

  About 15,100 people die each year from hepatitis C, making it the leading cause of chronic liver disease and liver transplantation.

The disease can be contracted through injection drug use, unprotected sex or through contact with the blood of someone who is infected. It can be minor, lasting only a few weeks, or a lifelong battle.

But a study from the University of Pittsburgh shows that hepatitis C could become a “rare” disease by 2036.

Controlling blood-loss is key when emergency responders on helicopters rush patients with traumatic injuries to the hospital.

That’s why University of Pittsburgh trauma experts are launching a trial to see if the blood-clotting drug,  tranexamic acid (TXA) could save lives by helping medics gain control of internal bleeding.

Could text messaging help reduce binge drinking among young adults?

A new study from the University of Pittsburgh School Of Medicine suggests that this might be the case.

According to the National Institute on Alcohol Abuse and Alcoholism Binge drinking is considered to be five drinks or more for men and  four drinks or more for women generally over a two hour period.

Brian Suffoletto, lead author of the study and an assistance professor of emergency medicine at Pitt, said binge drinking in the U.S. has become an epidemic.

Text messaging can serve a variety of purposes, from casually chatting with friends to ordering a pizza, but what about monitoring concussion symptoms?

Some, like researcher Stephanie Huang think it could be a tool for providing more personalized health care.

Thanks to a grant from the Pittsburgh Emergency Medicine Foundation, the first-year student from Rutgers Robert Wood Johnson Medical School is coming to Pittsburgh to see if texting is a more effective way of getting patients to monitor their own concussion treatments.

Healthcare providers often urge patients to be more involved in their own care, and now the University of Pittsburgh has begun a $300,000 competition to encourage people to show how they take charge.

Pitt Innovation Challenge, PInCh, would like people from all over to submit a two-minute video, by March 2, citing a health problem, such as high blood pressure, and create a solution that challenges people to take control of their healthcare.

A recent study from the University of Pittsburgh School of Medicine found that uninsured patients with a variety of common medical diagnoses were less likely to be transferred between hospitals for treatment.

The study came about because an “urban myth” that uninsured patients were more likely to be transferred persisted, yet there was no hard data to back it up.

ThyroSeq, a new way of genetically testing thyroid nodules for cancer, could save patients an extra procedure.

Developed at the University of Pittsburgh, ThyroSeq is a genetic sequencing test that allows researchers to accurately diagnose a thyroid growth for cancer.

Dr. Yuri Nikiforov, director of thyroid molecular diagnostics at the Pitt School of Medicine, said thyroid nodules typically appear as a lump on the neck close to the “Adam’s apple.” He said they are more common in women and the elderly.

Human papillomavirus (HPV) vaccines are one of the only vaccinations that can prevent cancer, but most women, especially black women, are still unlikely to get the shots. This is according to Sonya Borrero, assistant professor of medicine at the University of Pittsburgh School of Medicine.

A study from Borrero and researchers at the School of Medicine found black women are significantly less likely to receive human papillomavirus (HPV) vaccines than white women.

The University of Pittsburgh Medical Center and University of Pittsburgh School of Medicine plan to expand their Vascular Medicine Institute over the next five years, by creating the Heart, Lung Blood and Vascular Medicine Institute, or VMI.

Dr. Mark Gladwin, co-director of VMI, said it will be a hub for research.

"This will be the research home for scientists and physicians and physician scientists that have primary appointments within cardiology, pulmonary and hematology," he said.

When virologist and mother-to-be Carol Coyne was working in her lab four years ago, she began wondering how her placenta was protecting her unborn baby from the viruses she worked with.

At that time, placenta was seen as a passive barrier between a mother and her unborn child, but four years later, Coyne and director of Magee Woman’s Research Institute Yoel Sadovsky have uncovered a new purpose for it.

Sadovsky and Coyne have found that the cells in placenta, called trophoblasts, actually block viruses from crossing from the mother to her baby.

It is well known that uncontrolled bleeding can cause multiple organ failure and death.  It is also known that plasma reduces bleeding, so some are wondering if administering it early--while a patient is being transported to a hospital would lower mortality. 

That thought has prompted The University of Pittsburgh School of Medicine and UPMC to organize a four-year multi-center study of whether administering plasma to trauma victims on emergency helicopters will improve outcomes and save lives.

A small sampling of people living near Marcellus Shale development sites were found to have higher rates of perceived health problems and stress levels.

That’s according to a study done by researchers from the University of Pittsburgh Graduate School of Public Health. This was not a clinical study, but researchers said it could provide insight into effects of stress.

Researchers at the University of Pittsburgh School of Medicine have discovered a new biological pathway, or protein, that ramps up inflammation. They also have identified agents that can block it.

This could be effective in fighting the damaging inflammation that results from conditions such and pneumonia.