Juvenile Idiopathic Arthritis

Health
3:10 pm
Fri August 2, 2013

Pittsburgh Researchers Link Premature Aging Cells With Childhood Arthritis

Pittsburgh researchers have found the joints of children with chronic inflammatory arthritis contain immune cells similar to those of 90-year-olds.

A new study suggests premature aging of immune cells are linked to children with juvenile idiopathic arthritis (JIA).

The study, led by University of Pittsburgh professor of pediatrics and immunology Abbe de Vallejo, sampled immune cells called T-cells from 98 children with JIA.

The team found one-third of the T-cells in children had shortened “telomeres” that had reduced or lost the capacity to multiply.

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